Effect of administering activated lymphocytes originated from the dam on the immune cell reaction in Holstein calves

Injection of lymphokine activated killer (LAK) cells is known as useful for activation cellular immune system. Although the effect LAK has been clarified in human or mice, this on function not examined calves. Healthy ten Holstein calves were injected with 2 days after birth (LAK Group), and another eight observed controls (Control Group). All received colostrum formulation day birth, then, inoculated a live attenuated vaccine bovine herpesvirus (BHV)-1 at (the first vaccination) 6 second weeks birth. Peripheral blood their dam obtained 3 before calving was used preparation cells. Blood samples taken prior to inoculation inoculation, well vaccination from all Numbers CD8+ CD21+ increased significantly Group compared Control Group. The present study suggested improved injecting originated dams young BHV-1 vaccine.